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Fig 1.

Model schematic describing the patient pathway of the five treatment options for men with moderate-to-severe LUTS due to BPH.

Abbreviations: BPH, benign prostatic hyperplasia; CT, combination therapy; LUTS, lower urinary tract symptoms; PUL, prostatic urethral lift; PVP, photoselective vaporization of the prostate; TURP, transurethral resection of the prostate; WVTT, water vapor thermal therapy.

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Fig 1 Expand

Table 1.

Weighted average procedure costs, follow-up costs, subsequent retreatment costs, periprocedural AE costs, short- and long-term AE costs.

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Table 1 Expand

Table 2.

IPSS change from baseline to year 5 from the random-effects network meta‐analysis model for use in the base-case cost-effectiveness analyses.

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Table 2 Expand

Fig 2.

Medicare per patient costs at year 1 and year 5 for the five treatment options for men with moderate-to-severe lower urinary tract symptoms due to benign prostatic hyperplasia ranging from the least to the most expensive at year 1.

Abbreviations: CT, combination therapy; PUL, prostatic urethral lift; PVP, photoselective vaporization of the prostate; TURP, transurethral resection of the prostate; WVTT, water vapor thermal therapy.

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Fig 2 Expand

Table 3.

Costs, QALYs, and ICER at 5 years for the five treatment options for men with moderate-to-severe lower urinary tract symptoms due to benign prostatic hyperplasia.

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Table 3 Expand

Fig 3.

Scatterplots based on PSAs by comparing CT versus surgical treatments.

a: TURP vs. CT at 5 years. b: PVP vs. CT at 5 years. c: PUL vs. CT at 5 years. d: WVTT vs. CT at 5 years. Abbreviations: CT, combination therapy; PSA, probabilistic sensitivity analysis; PUL, prostatic urethral lift; PVP, photoselective vaporization of the prostate; QALYs, quality-adjusted life years; TURP, transurethral resection of the prostate; WVTT, water vapor thermal therapy.

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Fig 3 Expand