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Table 1.

Search terms used in the systematic searches for thermal, social, and immune-related stresses.

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Fig 1.

PRISMA flow diagram for thermal stress systematic search results.

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Fig 2.

Methods used to detect thermal stress indicators from the selected literature: (A) scan sampling; (B) video behavior classification.

Methods pooled in the “Others” domain are presented in the S2 Table in S1 File. Figure generated through rawgraphs.io.

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Fig 2 Expand

Fig 3.

Physiological markers used to evaluate thermal stress.

Other markers include: amino acids concentration; creatinine; gene expression; glutathione; lactate; myeloperoxidase; methylhistidine; and vitamin E. The comprehensive list of physiological markers found in the literature and the number of articles that used them are presented in the S3 Table in S1 File. Figure generated through rawgraphs.io.

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Fig 3 Expand

Fig 4.

PRISMA flow diagram for social stress systematic search results.

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Fig 5.

Methods to measure social stress included animal performance, animal vocalizations, physiological markers, cortisol levels, lesions, and social interactions.

Methods pooled in the “Others” domain are presented in the S5 Table in S1 File. (Source: rawgraphs.io).

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Fig 5 Expand

Fig 6.

Physiological markers, lesion assessment, and social behavior indicators found in the literature regarding the social stress model pulled from the databases.

Completed lists of the physiological markers, body lesion markers, and social behavior indicators are presented in the S6-S8 Tables in S1 File. Figure generated through rawgraphs.io.

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Fig 6 Expand

Fig 7.

PRISMA flow diagram for immune-related stress systematic search results.

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Fig 7 Expand

Fig 8.

Animal-based indicators used in the literature from the systematic search for the immune-related stress model.

Methods pooled in the “Others” domain are presented in the S10 Table in S1 File. Figure generated through rawgraphs.io.

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Fig 9.

Immune challenges identified in the literature from the systematic review.

Figure generated through rawgraphs.io.

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Table 2.

Primary indicators and measurement techniques of each stress model, presented based on the indicator type.

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Table 2 Expand