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Fig 1.

Participant flow chart.

Index test = initial histological sample with non-atypical endometrial hyperplasia between 2000–2015. a) One woman did not want to participate in office mini-hysteroscopy, but she completed the transvaginal ultrasound and the interview.

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Table 1.

Results of biopsies from office mini-hysteroscopy at follow-up.

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Table 2.

Participant characteristics.

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Table 3.

Results on follow-up of women who had a hysterectomy within 3 months of initial diagnosis of non-atypical endometrial hyperplasia.

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Fig 2.

Subsequent atypical hyperplasia or endometrial carcinoma presented in all women with non-atypical hyperplasia (left) and according to WHO 1994 classification type of non-atypical hyperplasia (right). The endpoint was atypia or carcinoma. Women were censored (black lines) due to hysterectomy, follow-up biopsy, or death. The women in whom follow-up biopsies were not obtained or in whom the biopsy material obtained was insufficient for diagnostic evaluation were censored on the day of their follow-up clinical examination.

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Table 4.

Results of follow-up in women who remained at risk more than three months after initial diagnosis of non-atypical endometrial hyperplasia.

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