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Fig 1.

PRISMA flow diagram of the study selection for the systematic review and meta-analysis.

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Table 1.

Characteristics of the included studies.

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Fig 2.

Forest plots of the effects of oral vitamin A supplementation in preterm infants.

(A) Duration of mechanical ventilation (days); (B) Duration of CPAP/HHFNC (days); (C) Duration of oxygen requirement (days); (D) Moderate-to-severe BPD at 36 weeks PMA; (E) Oxygen requirement at 36 weeks PMA; (F) Postnatal steroids needed.

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Fig 2 Expand

Fig 3.

Forest plots of the effects of oral vitamin A supplementation in preterm infants and adverse effects.

(A) Death; (B) Duration of hospitalization (days); (C) Oxygen requirement at 28 days of age; (D) ROP requiring treatment; (E) Serum retinol concentration at 28 days of age (μg/dL); (F) Vomiting.

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Fig 3 Expand

Table 2.

GRADE summary of findings: Effects of oral vitamin A supplementation on clinical outcomes in preterm infants.

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Table 2 Expand