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Fig 1.

Study flow chart.

Consort flow chart of patients screened.

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Table 1.

Patient characteristics.

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Table 1 Expand

Fig 2.

Scatter plot of measured and expected MAP after fluid bolus.

Scatter plot comparing measured and expected MAP after fluid bolus. Line represents perfect fit. MAP = Mean arterial pressure.

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Fig 2 Expand

Fig 3.

Scatter plot of measured and expected UO one hour after fluid bolus.

Scatter plot comparing measured and expected UO one hour after fluid bolus. Line represents perfect fit. UO = Urine output.

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Fig 3 Expand

Table 2.

Accuracy of expectations.

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Table 2 Expand

Fig 4.

Boxplot of difference between measured and expected MAP by indication for bolus.

Boxplot showing difference between expected and measured MAP by main reason for administration of fluid bolus. Positive values indicate a higher value for expected MAP compared to measured, and the inverse for negative values. MAP = Mean arterial pressure. CVP = Central venous pressure. ScvO2 = Central venous oxygen saturation. ScvO2 = Mixed venous saturation.

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Fig 4 Expand

Fig 5.

Boxplot of difference between measured and expected UO by indication for bolus.

Boxplot showing difference between expected and measured MAP by main reason for administration of fluid bolus. Positive values indicate a higher value for expected UO compared to measured, and the inverse for negative values. UO = Urine output. CVP = Central venous pressure. ScvO2 = Central venous oxygen saturation. ScvO2 = Mixed venous saturation.

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Fig 5 Expand

Table 3.

Triggers for FBT and physiological expectations.

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Table 3 Expand

Table 4.

Effects of the fluid bolus.

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Table 4 Expand