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Table 1.

Demographic and baseline data* for ME/CFS patients and controls.

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Table 2.

Cardiopulmonary responses at the gas exchange threshold during exercise testing in ME/CFS patients and controls.

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Table 2 Expand

Table 3.

CPET variables of ventilatory and heart rate performance during exercise testing in ME/CFS patients and controls.

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Table 3 Expand

Table 4.

Cardiopulmonary responses at peak exercise in ME/CFS patients and controls.

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Fig 1.

Mean (95% CI) cardiopulmonary exercise testing values for participants with ME/CFS and otherwise healthy controls.

Plots in the left column show values for the full study sample (ME/CFS = 178; Controls = 169) and plots in the right column show values for the fitness-matched subgroup (ME/CFS = 99; Controls = 99). Data are expressed as 20, 40, 60, 80, and 100% of peak oxygen uptake. Significant findings from the linear mixed effects models of the entire exercise response are denoted with *. a. Ventilatory parameters—ventilation (), respiratory frequency (fR), and tidal volume (VT). b. Heart rate parameters—heart rate (HR), oxygen pulse (), and chronotropic index (CTI). c. Efficiency related parameters—ventilatory equivalent for oxygen (), ventilatory equivalent for oxygen (), and oxygen uptake/work rate (). d. Ratings of perceived exertion (RPE) on the Borg 6–20 scale.

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Fig 1 Expand