Fig 1.
Patient flowchart.
Fig 2.
Venn Diagram showing the number of patients with sepsis by Sepsis-2 (N = 2040) or Sepsis-3 (N = 1295) criteria or both (N = 1074) and the numbers of genes and genetic variants associated with each sepsis phenotype.
Fig 3.
Manhattan plot showing the single nucleotide polymorphisms and their univariate p-values for Sepsis-2.
Fig 4.
Manhattan plot showing the single nucleotide polymorphisms and their univariate p-values for Sepsis-3.
Fig 5.
Calibration plot showing the fraction of patients with sepsis for each decile of risk calculated from the polygenic risk score.
Sepsis-2 (left), Sepsis-3 (right).