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Fig 1.

PICO(S) search strategy.

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Fig 2.

PRISMA diagram.

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Table 1.

Study characteristics.

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Table 2.

Mortality associated with perioperative hypotension.

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Table 3.

Mortality associated with perioperative hypertension.

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Table 4.

Mortality associated with perioperative variability in blood pressure (and other measures of blood pressure).

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Table 5.

Acute kidney injury and other renal outcomes associated with perioperative hypotension.

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Table 6.

Stroke associated with intraoperative hypotension.

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Table 7.

Delirium associated with perioperative hypotension.

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Table 8.

Delirium associated with perioperative hypertension.

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Table 9.

Cardiovascular and cerebrovascular outcomes associated with perioperative hypotension.

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Table 10.

Cardiac and cerebrovascular outcomes associated with perioperative hypertension.

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Table 11.

Diverse outcomes associated with perioperative hypotension.

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Table 12.

Diverse outcomes associated with perioperative hypertension.

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Table 13.

Diverse outcomes associated with perioperative control of mean arterial pressure and blood pressure variation.

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