Table 1.
Active compounds in HQ.
Fig 1.
33 overlapped target genes were from three databases (TCMSP, CTD and GeneCards).
Fig 2.
The Compound-target network of HQ. The blue circle is the compound and the purple triangle is the target protein.
Table 2.
Active compounds in HQ.
Fig 3.
33 overlapped target genes were used to constructed PPI network and hub genes in PPI network. The purple triangle is the target protein. The size of the triangle represents the weight of the target protein.
Fig 4.
33 overlapped genes were analysis by GO annotation. BP/CC/MF are all shown in the figure, the specific meaning can be seen in the text under the bar graph.
Fig 5.
33 overlapped genes was analysis by KEGG, which enriched in 24 pathways. The darker the color, the greater the weight, and the larger the circle, the greater the genenumber.
Fig 6.
Prostate cancer pathway information generated by KEGG. The highlighted part of the pathways and protein nodes related to this research.
Table 3.
GO.
Fig 7.
The expressions of 5 targets in prostate tissues of cancer patients and normal people.
Fig 8.
Survival analysis of five core proteins.
Survival analysis involves five core proteins. The blue line in the figure indicates the survival of prostate cancer patients whose targets had not changed. Non-blue lines show changes in the survival of prostate cancer patients with changed targets.
Fig 9.
Survival analysis involves AR gene. The blue line in the figure indicates the survival of prostate cancer patients whose targets had not changed. Non-blue lines show changes in the survival of prostate cancer patients with changed targets.
Table 4.
Molecular docking.
Fig 10.
Core targets molecular docking.
Core targets molecular docking. The meaning of colors and graphics can be known from the legend.