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Fig 1.

Inclusion chart of patients.

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Fig 2.

Automated lobe segmentation process and quantification of emphysema per lobe in a 45-year-old woman with COVID-19 pneumonia.

(a./b./d.) Sequential segmentation of airways, lungs, and lobes. (c) Results of volumetric measurement of emphysema in both lungs, each lung, and each lobe (attenuation threshold of voxels, <-950 HU). Emphysematous voxels are shown in red. Reprinted under a CC BY license, with permission from Philips Healthcare, original copyright [2021].

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Fig 3.

ROI measurements.

Manual ROI measurements in the left upper lobe of a 45-year-old woman with COVID 19 pneumonia at initial CT scan (a.) and at follow-up CT scan after 45 days (b.), a decreasing in attenuation values by -27 HU can be seen between initial scan and follow-up.

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Table 1.

Demographic characteristics of n = 32 patients with RT-PCR proven coronavirus disease.

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Table 2.

Demographic characteristics and quantitative measurements of n = 32 patients with RT-PCR proven coronavirus disease categorized by follow-up interval </> 30 days.

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Fig 4.

Boxplot for emphysema volume.

Automated measured significantly higher amount of emphysema volume in follow-up CT scans >30 days as compared to the initial CT scan.

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Fig 5.

Boxplot for attenuation values.

Manually measured attenuation values by ROIs in unaffected lung areas show no differences in the groups >30 days and < 30 days between initial CT scan (white) and follow-up CT scans (grey).

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