Fig 1.
Babies eligible for the study were admitted to the neonatal Intensive Care Unit for consideration of hypothermia treatment for moderate-to-severe hypoxic-ischemic encephalopathy. Healthy babies with no perinatal problems matched for gestational age, birth weight, sex, and date of birth were selected for the control group.
Fig 2.
Representative MRI scans showing altered studies in two hypoxic-ischemic newborns.
In A, the MRI scan performed at postnatal day 5 in a female (39 weeks of gestational age) showed increased signal in both temporal lobes using Diffusion-Weighed Images; scan performed in the same patient aged 30 months showed no abnormalities (B). In C, the MRI scan performed at postnatal day 5 in a male (41 weeks of gestational age) showed linear hyperintensity in left insular subcortical area using T1-Weighed Images; scan performed in the same patient aged 26 months showed no abnormalities (D).
Table 1.
Demographic data of control group and NHIE group children.
Table 2.
Results from testing with the ASQ3.
Table 3.
Results from testing with the CBCL 1.5–5.
Table 4.
Correlation between developmental assessment and contextual factors and items of mood disturbances in NHIE group children.