Fig 1.
Histologic examination of core needle biopsies.
A case representing two core needle biopsies examined using three step sections in (a). Core needle biopsy in (b) representing three cores showing tumor infiltration from 20% to 80% (arrows).
Fig 2.
Peritumoral inflammation and lymphovascular space invasion.
Squamous cell carcinoma with strong peritumoral inflammtory response with lymphocytic (a) and eosinophilic (b) predominance. Multiple lymphovascular involvement (arrows) is shown in (c). Intravascular tumor cell surrounded by lymphoepithelial cells in lymphovascular space invasion can be seen in (d).
Table 1.
Patient- and tumor characteristics.
Table 2.
Multivariable logistic regression model for correct assessment of lymphovascular space invasion (LVSI) and tumor grading.