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Fig 1.

Typical single-channel CNN architecture.

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Fig 2.

Multi-channel Xception-based thyroid cancer detection framework.

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Fig 3.

Single input dual-channel model.

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Fig 4.

Double inputs dual-channel model.

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Fig 5.

Double inputs dual-channel (four-channel) model.

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Fig 6.

Ultrasound images from DDTI: TIRADS 2 on the left-side with well defined margins and no calcification, labeled as “benign”; TIRADS 5 on the right-side with micro-calcification, labeled as “malignant”.

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Fig 7.

Segmented thyroid gland CT scans from patient No. 277: Left-side is Goiter (Benign) and right-side is Papillary Cancer (Malignant).

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Table 1.

Data sets descriptions.

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Table 2.

Comparison of various CNN models in binary classification tasks: Different sources of ultrasound images were applied for thyroid cancer detection.

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Table 3.

Comparison of different CNNs on thyroid cancer diagnosis via CT.

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Fig 8.

Initial binary classification task running time comparison for the 11 models.

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Table 4.

Single-channel and dual-channel comparison.

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Table 5.

DIDC and four-channel comparison.

Class 0 to 3 indicates the patient either has normal thyroid (0), has malignant left-side thyroid (1), has right-side thyroid malignant (2), or has both sides malignant (3).

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Fig 9.

DIDC and four-channel 10-fold cross-validation accuracy results.

The average 10-fold scores for each epochs were demonstrated using the black line, and the average testing accuracy for DIDC is 0.95, for four-channel is 0.94.

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Table 6.

Experiments comparison with existing literature.

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