Table 1.
Characteristics of trial cohort.
Fig 1.
Flow diagram for trial design quality of Phase 2/3 and Phase 3 SARS-CoV-2 trials.
a) Refers to trial that is either placebo-controlled or has a standard of care comparator arm. b) Refers to a treatment trial with a clinical primary outcome or a prevention trial with either a clinical primary outcome or laboratory-confirmed SARS-CoV-2.
Table 2.
Evaluation of design quality of trials meant to inform clinical practice.
Table 3.
Stratified analysis of redundancy, design, trial feasibility and informativeness by sponsor, country location, trial type, number of trial centers.