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Fig 1.

Muscle hydrolysis method.

An illustration of methodology for hydrolysis of Bighead carp muscle using endogenous digestive enzymes from adult LMB.

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Table 1.

Formulations and proximate and amino acid composition of experimental diets.

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Fig 2.

SDS-PAGE of Bighead carp muscle hydrolysate.

10% T denaturing SDS PAGE of Bighead carp muscle hydrolysate obtained using adult largemouth bass endogenous digestive enzymes. The treatments presented are as follows: Lane 1—LAD–protein ladder (marker; 200–10 kDa from top to bottom); Lane 2-CNTL–control, muscle homogenate and enzymatic cocktail mix after heat shock, no enzymatic digestion; Lane 3-Blank–electrophoretic blank sample; Lane 4-SD–stomach digestion, muscles enzymatically hydrolyzed in acid pH; Lane 5-B-ID–blank intestinal digestion, muscles incubated in acid and alkaline pH without LMB digestive enzyme extract; Lane 6-Blank–electrophoretic blank sample; Lane 7-ID–intestinal digestion, muscles enzymatically hydrolyzed in acid and alkaline pH; Lane 8-B-SD–muscles incubated in acid pH without LMB digestive enzyme extract; Lane 9, 10—LAD–protein ladder.

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Table 2.

Treatment effect on growth performance and survival measures.

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Fig 3.

Occurrence of individual skeletal deformities.

The individual skeletal deformities in LMB fed control diet (intact muscle protein-based) and Bighead carp muscle hydrolysate-based diet. The black dots represent individual data points from the replicate tanks. Different letters indicate statistical difference at p>0.05.

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Fig 4.

Total skeletal deformities.

Percentage of total skeletal deformities in LMB fed control diet (intact muscle protein-based) and Bighead carp muscle hydrolysate-based diet. The black dots represent total skeletal deformities from the replicate tanks. Different letters indicate statistical difference at p<0.05.

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Fig 5.

Free glycine levels in LMB muscle.

Muscle free glycine levels in LMB after 3 weeks of feeding Control diet (non-hydrolyzed Asian carp muscle-based) and Hydro diet (50% Asian carp muscle hydrolysate-based). The bars represent free glycine level 3-hours after feeding. The line indicates free glycine physiological baseline. The black dots represent average free glycine levels from the replicate tanks. Different letters indicate statistical difference at p<0.05.

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Fig 6.

Muscle free amino acid levels in LMB.

Muscle free amino acid levels in LMB after 3 weeks of feeding Control diet (non-hydrolyzed Asian carp muscle-based) and Hydro diet (50% Asian carp muscle hydrolysate-based). The bars represent free amino acid levels 3-hours after feeding. The line indicates FAA physiological baseline. The black dots represent the free FAA levels from the replicate tanks. Different letters indicate statistical difference at p<0.05.

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Table 3.

Postprandial muscle free amino acid levels in LMB.

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