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Fig 1.

Serum levels of steroids (overall view).

Serum levels of 3βAdiol (A), Δ5-diol (B), DHEA (C), and E2 (D) in young men aged 20–45, elderly men over 55 years old, young women aged 20–45 at three time-points in their menstrual cycle (EFP, Midcycle, and MLP), and elderly women over 55 years old. Data on elderly men and women are from our previous publication [8]. Median serum levels of each steroid are indicated in each box using horizontal bars. The vertical bars indicate the range, and the horizontal boundaries of each box represent the first and third quartiles. **** p<0.0001 as compared between young men and women; # p<0.05, #### p<0.0001 as compared during the menstrual cycle (at EFP, Midcycle, and MLP); †† p<0.01, ††† p<0.001, †††† p<0.0001 as compared between young and elderly subjects. Abbreviations: 3βAdiol, 5α-androstane-3β,17β-diol; Δ5-diol, androstenediol; DHEA, dehydroepiandrosterone; E2, 17β-estradiol; EFP, early follicular phase; Midcycle, mid-cycle phase; MLP, mid-luteal phase.

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Fig 1 Expand

Table 1.

Serum steroid levels at three time-points in the menstrual cycle.

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Table 2.

Scores on depression rating scales during the menstrual cycle.

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Table 3.

Sex differences in serum steroid levels.

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Table 3 Expand

Table 4.

Sex differences in scores on depression rating scales.

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Table 5.

Comparison of steroid levels between young men and elderly men.

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Table 6.

Comparison of steroid levels between young women and elderly women.

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Table 6 Expand