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Fig 1.

Flowchart depicting availability of data for our analyses.

LC-MS/MS: Liquid chromatography-tandem mass spectrometry.

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Fig 1 Expand

Fig 2.

Differences in 25(OH)D levels between carriers and non-carriers of DBP related risk alleles.

25(OH)D levels at baseline (N = 26) (A) and after 48 weeks of supplementation (N = 20) (B), compared between non-carriers (left group) and carriers (right group) of the rs4588 and rs7041 risk alleles. P-value shown is calculated using a Mann-Whitney U test. Triangles indicate calculated data, derived from immunoassay values to replace missing values from the LC-MS/MS method.

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Fig 2 Expand

Table 1.

Baseline characteristics of the studied participants.

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Table 1 Expand

Fig 3.

Differences in 25(OH)D levels between carriers and non-carriers of CYP related MS risk alleles.

25(OH)D levels at baseline (N = 26) (A) and after 48 weeks vitamin D3 supplementation (N = 20) (B), compared between non-carriers (left group) and carriers (right group) of the rs12368653 and rs2248359 risk alleles. P-value shown is calculated using a Mann-Whitney U test. Triangles indicate calculated data, derived from immunoassay values to replace missing values from the LC-MS/MS method.

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Fig 3 Expand