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Fig 1.

Study flow chart.

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Table 1.

Baseline characteristics of critically ill patients on the first voriconazole therapeutic drug monitoring.

Data presented are means +/- standard deviations or numbers and corresponding percentages (%).

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Fig 2.

Correlation between SOFA score and voriconazole trough levels.

The dots represent the individual pairs for the X–Y variables. The straight line is the linear regression line.

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Fig 2 Expand

Table 2.

Univariable and multivariable analyses of variables potentially associated with voriconazole trough concentration.

Data presented are β coefficients (95% CI) and their corresponding P values.

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Table 2 Expand

Fig 3.

Box plots of voriconazole trough levels according to the presence or absence of adverse effects.

For each box of the box plots, the centre line represents the median, the bottom line represents the 25th percentiles and the top line represents the 75th percentiles. The whiskers of the box plots show 1.5 interquartile range (IQR) below the 25th percentiles and 1.5 IQR above the 75th percentiles, and outliers are represented by small circles.

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