Table 1.
Characteristics of the study population.
Fig 1.
Comparison between the numbers of abnormalities detected per case by virtual autopsy and conventional autopsy considering the anatomic segments.
The mean number of abnormalities detected per case using virtual autopsy at 3 T and classic autopsy for each anatomic segment considered was evaluated using p value.
Table 2.
Statistical analysis of the diagnostic utility of virtual autopsy at 3 T compared to the classic autopsy related to the fetal anatomical segments evaluated by standard protocol.
Fig 2.
Correlation between virtual autopsy score (VA score), classic autopsy score (CA score) and various parameters.
Linear regression line and its 95% confidence interval, Spearman correlation coefficient (r) and significant (p). a) correlation between CA and VA score with fetal body weight; a’) correlation between CA and VA score with gestational age; b) correlation between diagnostic error score (DgE_score) with fetal body weight; b’) correlation between DgE_score with gestational age; c) correlation between VA using pm-MRI at 3T diagnostic score with CA diagnostic score.
Table 3.
Correlation between diagnostic score (DgE_score) on each anatomic segment and gestational age and fetal body weight.
Table 4.
Diagnostic utility of pm-MRI 3 T compared to conventional autopsy, considering the prenatal indication for therapeutic interruption of pregnancy.
Table 5.
Description of fetal anomalies detected by ultrasound in every group included in the study.
Fig 3.
Comparison between post mortem MRI at 3T, T2 WI and conventional autopsy of a 22 weeks of gestation fetus with Dandy Walker malformation.
The images depict enlarged posterior fossa, cystic dilatation of the fourth ventricle extending posteriorly, and vermis hypoplasia.
Fig 4.
22 weeks of gestation fetus diagnosed prenatally with a), a’) fast growing sacroccigian teratoma. b), b’) pm-MRI at 3 T with injection of gadolinium substance depicting moderate vascularization in the tumor, T2 and T1 WI, sagittal section c),c’) confirmation of the imaging findings by conventional autopsy.
Fig 5.
23 weeks of gestation plurimalformed fetus diagnosed prenatally with 18 trisomy.
a) prenatal ultrasonography; b) pm-MRI at 3 T, T2 WI sagittal section, demonstrating hydrops fetalis, hygroma, partial corpus callosum agenesis and limbs malformations; c) macroscopic examination of the fetus.