Table 1.
Clinical and biological data of patients with amyotrophic lateral sclerosis.
Table 2.
A: The association between NfL in CSF and clinical characteristics of ALS patients (n = 70).
B: The association between NfL in plasma and clinical characteristics of ALS patients (n = 49).
Table 3.
A: The association between TDP-43 in CSF and clinical characteristics of ALS patients (n = 70).
B: The association between TDP-43 in plasma and clinical characteristics of ALS patients (n = 49).
Table 4.
A: The association between t-tau in CSF and clinical characteristics of ALS patients (n = 69).
B: The association between t-tau in plasma and clinical characteristics of ALS patients (n = 48).
Fig 1.
Correlation of inter-biomarker levels in CSF and plasma.
Levels of individual biomarkers in ALS patients are presented as logarithms. The rs and p-values generated by Spearman’s rank correlation tests are shown. The combinations of biomarkers in CSF are presented in A-C and those in plasma are in D-F. Correlations between the same markers in CSF and plasma were presented in our previous report [11]. A linear regression line is presented when there is a significant correlation. CSF, cerebrospinal fluid; NfL, neurofilament light; TDP-43, TAR DNA-binding protein 43; t-tau, total tau; ALS, amyotrophic lateral sclerosis.