Table 1.
Primers for qPCR.
Fig 1.
Effect of IOP on the histopathology of endometritis.
(a). Control group. Local exfoliation of endometrial epithelial cells (black arrow). (b). LPS group. A small number of endometrial and glandular epithelial cells were swollen, the cytoplasm was loose and light stained (yellow arrow), and the lamina propria was heavily congested and dilated (blue arrow). (c). LPS+IOP Group. Local endometrial epithelium narrowed and a few endometrial epithelial cells shed (red arrow). (Hematoxylin and eosin staining, magnification 200 ×).
Fig 2.
Effects of IOP on inflammatory cytokines TNF-α, IL-6, IL-1β.
Mean ±SD was used for data processing. Three replicates were processed in each group. #P < 0.05 vs. Control group, *P < 0.05vs. LPS group.
Fig 3.
The total structure of the gut microbiota.
(a). Shannon index of α diversity analysis. (b). Simpson index of α diversity analysis, ns means no difference. (c). Principal Co -ordinates analysis (PCoA) of β diversity.
Fig 4.
Changes in gut microbiota composition.
(a). Species relative abundance of species at the phylum level. (b). Species relative abundance of species at the genus level. (c). Boxplot representing differences at the phylum level. (d). Heat map of differences at the genus level. Red indicates relatively high species abundance and blue indicates relatively low species abundance. (e). Significant species differences among the control group, LPS group and IOP interference group. #P < 0.05, ##P < 0.01,vs. Control group, **P < 0.01, ***P < 0.001vs. LPS group.