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Fig 1.

Flow diagram describing the study selections from literature searching.

*Update values.

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Table 1.

Plant part and type of extract from L. ferrea overview used in vivo and in vitro studies.

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Table 2.

Data from in vivo studies included.

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Table 3.

Data from outcomes of in vivo studies included.

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Table 4.

General characteristics of in vitro studies.

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Table 5.

Outcome description from the in vitro studies.

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Table 6.

Risk of bias in vivo studies according to SYRCLE’s RoB tool of the ten studies included in the systematic review.

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Table 7.

Certainty of evidence from in vivo studies.

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Fig 2.

Reporting quality in in vitro studies.

A. L. ferrea fruits quality reporting on in vitro study. B. L. ferrea leaves quality reporting on in vitro study. C and D. L. ferrea stem bark quality reporting on in vitro study. Grey: not determined; green bar: fulfilled; yellow bar: partially fulfilled; red bar: not fulfilled.

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