Fig 1.
The comprehensive therapeutic protocol for hepatoblastoma.
Fig 2.
Overall survival (OS) curves of children with hepatoblastoma in each cohort.
(A) OS curve of entire cohort in 197 children. (B) Comparison of OS curves between complete remission (CR) group and non-CR group. (C) Comparison of OS curves among non-recurrence group, recurrence group, and non-CR group. (Kaplan-Meier method, P value shown for Log-rank test between variables).
Table 1.
Comparison of OS rates in each cohort of children with hepatoblastoma.
Table 2.
Clinical features of 140 children with initial CR.
Fig 3.
Overall recurrence-free survival (RFS) and comparisons of RFS by age, sex, pathologic type, PRETEXT stage, metastatic disease, vascular involvement, surgical margin status, and serum AFP level.
(A) Overall RFS. (B) Comparison of RFS by age. (C) Comparison of RFS by sex. (D) Comparison of RFS by pathologic type. (E) Comparison of RFS by PRETEXT stage. (F) Comparison of RFS by metastatic disease. (G) Comparison of RFS by vascular involvement. (H) Comparison of RFS by surgical margin status, including macroscopically positive margin (MacroPM), microscopically positive margin (MicroPM), and microscopically negative margin (MicroNM). (I) Comparison of RFS by serum AFP level. (Kaplan-Meier method, P value shown for Log-rank test between variables).
Table 3.
Comparison of RFS in each cohort of 140 children with initial CR.
Table 4.
Cox proportional hazard model for the independent risk factors of recurrence in 140 children with initial CR.