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Table 1.

Basic characteristics of participants at admission.

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Fig 1.

Comparison of platelet, IPF% and IPF# among dengue, confirmed CABI, and suspected CABI groups at admission.

Horizontal lines show the median and interquartile ranges. (A) shows a comparison including all participants and (B) shows a comparison including only the subgroups with severe thrombocytopenia <50×103/μL at admission. Comparison of dengue, confirmed CABI and suspected CABI groups were performed using Kruskal-Wallis test followed by the Dunn’s post hoc test with Holm adjustment. *: P<0.05, †: P<0.01, ‡: P<0.001. CABI: community acquired bacterial infection, IPF%: Immature Platelet Fraction, IPF#: Immature Platelet Fraction Count.

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Fig 2.

Time course trends of platelet parameters in each group from the first to tenth days of illness.

Box and whisker plots show the time course trends of platelet parameters in each group from the first to tenth days of illness. Boxes show the median and interquartile values, whiskers represent the upper and lower adjacent values and dots indicate outside values. The total numbers of evaluations included on each day are indicated on the X axis by each group. CABI: community acquired bacterial infection, IPF%: Immature Platelet Fraction, IPF#: Immature Platelet Fraction Count.

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Fig 3.

Comparison of platelet parameters among dengue, confirmed CABI, and suspected CABI groups by specific time-phases.

Box and whisker plots show the platelet parameters of dengue, confirmed CABI, and suspected CABI groups observed in specific time-phases: febrile phase (day 1 to 3), critical phase (day 4 to 6), and recovery phase (day 7 to 10). (A) shows a comparison including all participants and (B) shows a comparison including only the subgroups with severe thrombocytopenia defined as platelet nadir <50×103/μl during hospitalization. Boxes show the median and interquartile values, whiskers represent the upper and lower adjacent values and dots indicate outside values. Comparison of dengue, confirmed CABI, and suspected CABI groups were performed using the Kruskal-Wallis test followed by the Dunn’s post hoc test with Holm adjustment. *: P<0.05, †: P<0.01, ‡: P<0.001. CABI: community acquired bacterial infection, IPF%: Immature Platelet Fraction, IPF#: Immature Platelet Fraction Count.

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Fig 3 Expand

Fig 4.

Comparison of platelet parameters between the severe and non-severe dengue thrombocytopenia groups by specific time-phases.

Box and whisker plots show the platelet parameters of the severe thrombocytopenia dengue group defined as platelet nadir <50×103/μl during hospitalization and the non-severe thrombocytopenia dengue group defined to include all patients with a platelet nadir ≥50×103/μl during hospitalization observed in specific time-phases: febrile phase (day 1 to 3), critical phase (day 4 to 6), and recovery phase (day 7 to 10). Boxes show the median and interquartile values, whiskers represent the upper and lower adjacent values and dots indicate outside values. The comparison between each pair of dengue subgroups were performed using the Mann Whitney test. *: P<0.05, †: P<0.01, ‡: P<0.001. IPF%: Immature Platelet Fraction, IPF#: Immature Platelet Fraction Count.

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Fig 4 Expand