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Fig 1.

Disc photographs from two WHISE participants, outlining vertical disc and cup diameters with cup-to-disc ratio < 0.6 (A), and cup-to-disc ratio 0.6 (B).

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Fig 2.

Schema: Diagram of analysis of patient population.

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Table 1.

18 candidate SNPs associated with vertical cup-to-disc ratio.

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Table 2.

Final 13 SNPs included in weighted genetic risk score based on high imputation quality (R2) and matching risk alleles.

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Fig 3.

Comparison of 3MSE scores by large cup-to-disc ratio.

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Fig 4.

Comparison of weighted genetic risk score by large cup-to-disc ratio.

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Table 3.

Patient demographic and clinical characteristics by large cup-to-disk ratio.

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Table 4.

Linear regression model estimates of 3MSE scores.

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