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Fig 1.

DTS233 visual interpretation [22].

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Fig 2.

Decision tree.

The square decision node indicates the decision point between the two arms; circular chance nodes show points where two alternative events for a patients are possible [35]. Branches emanating from each chance node indicate possible events and the sum of their probabilities must equal 1; and triangular terminal nodes are at the ends of pathways and represent the outcome of interest [36]. Recommended treatments are green and incorrect treatments are red. Pathways are mutually exclusive sequences of events [35].

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Table 1.

Model inputs.

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Table 2.

Deterministic ICERs for healthcare delivery, societal and scenario analysis.

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Fig 3.

Univariate sensitivity tornado diagram–scenario analysis: Societal perspective (including cost of AMR).

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Table 3.

Univariate sensitivity analysis–scenario analysis: Societal perspective (including cost of AMR).

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Fig 4.

Probabilistic sensitivity analysis (health sector perspective): Scatter plot of incremental health sector cost and incremental effect resulting from replacing current clinical practice by POCCRP testing.

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Fig 5.

Probabilistic sensitivity analysis (societal perspective): Scatter plot of incremental health sector cost and incremental effect resulting from replacing current clinical practice by POCCRP testing.

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Fig 6.

Probabilistic sensitivity analysis (scenario analysis—societal perspective including economic cost of AMR): Scatter plot of incremental health sector cost and incremental effect resulting from replacing current clinical practice by POCCRP testing.

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Fig 7.

Cost-effectiveness acceptability curves.

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