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Fig 1.

CONSORT flow diagram.

Flow of participants beginning with all potentially eligible individuals, those enrolled and then those included in the 4 month, 1-year and 3-year analyses.

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Table 1.

Demographic characteristics at baseline of monitored individuals and matched controls.

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Fig 2.

Atrial fibrillation diagnosis.

A.) Cumulative Probability of a diagnosis of atrial fibrillation in the 3 years following the initiating of monitoring. B.) Rate of new diagnosis of atrial fibrillation in the monitored and observational cohorts after completion of active monitoring. All new diagnoses occurring annually after 6 months from the initiation of screening.

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Fig 3.

Primary endpoint.

Cumulative incidence of the combined primary endpoint of death, stroke, systemic emboli or myocardial infarction in actively monitored and observational control cohorts over the 3 years following initiation of screening.

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Table 2.

Unadjusted and adjusted clinical outcomes at 3 Years.

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Table 2 Expand

Fig 4.

Primary endpoint in those receiving a new diagnosis of atrial fibrillation.

Cumulative incidence of the combined primary endpoint in individuals diagnosed with atrial fibrillation in A.) the actively monitored and observational control cohorts, and B.) the actively monitored cohort based on whether their initial diagnosis of AF was via ECG patch screening or via a clinical diagnosis, and the observational control cohort.

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Fig 5.

Clinical events surrounding a new atrial fibrillation diagnosis.

Clinical Events in the two weeks preceding and the 2 weeks following a new atrial fibrillation (AF) diagnosis, inclusive of the diagnosis date, in the observational cohort and the actively monitored cohort based on whether their initial diagnosis of AF was via ECG patch screening or via a clinical diagnosis.

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