Table 1.
Assessment of general data between study groups.
Table 2.
Assessment of clinical data between study groups.
Table 3.
Laboratory tests and analysis of data between study groups.
Fig 1.
Gross pathology of macroscopic hemorrhages.
1. Hemorrhage in the putamen; 2. Extensive hemorrhage in temporal lobe; 3. Punctate hemorrhages in cerebral peduncles; 4. Lateral ventricle filled by blood; 5. Focal hemorrhage in cerebellar cortex; 6. Punctate hemorrhages in middle cerebellar peduncles.
Fig 2.
Gross pathology of macroscopic hemorrhages.
7. Hemorrhage in corpus callosum; 8. Hemorrhages in forceps major (occipitalis); 9. Extensive hemispheric hemorrhage, with intense deviation from the midline.
Table 4.
Distribution of macroscopic hemorrhages and vascular impairment.
Fig 3.
Microscopic thrombo-hemorrhagic alterations and systemic complications.
Intraparenchymal hemorrhage due to rupture of the vascular wall (black arrowhead, A). Intraparenchymal hemorrhage with discrete inflammatory infiltrates of neutrophils (black arrowhead), lymphocytes and histiocytes (B). Thrombi in a large vessel (C), causing pulmonary infarct (D and E), with microthrombi in cerebral parenchyma (black arrowhead, F). Petechial hemorrhage with wall vessel necrosis (G). (hematoxylin and eosin. A: 100x, B: 200x, C: 100x, D: 200x, F: 400x, G: 200x).
Fig 4.
Inflammatory cells and reaction processes in the examined brains.
Lymphocytes (arrowhead) forming bulky perivascular cuffing (H). Macrophages (arrowhead), red cell diapedesis and edema around blood vessels (I). Microglial nodule (microglia cell, arrowhead) (J). Occurrence of intraparenchymal hemorrhagic phenomenon without association with inflammatory process (K). (hematoxylin and eosin. H: 400x, I: 200x, K: 200x).
Table 5.
Hemorrhagic and thrombotic manifestations: Patterns and distributions.