Fig 1.
Study design for assessing the comparative effectiveness of A-GPS intervention via an RCT with stratified randomization (see S1 File. The Design and Implementation of Asthma-Guidance and Prediction System (A-GPS) for the definition for each stratum for details).
Fig 2.
A-GPS report for individual patients provided to Primary Care Providers (PCPs) quarterly.
Fig 3.
Consort flow diagram for subject enrollment and random allocation of subjects in each stratum to intervention vs control group (see Fig 1 for randomization, intervention and follow up).
Table 1.
Baseline characteristics of study subjects between the intervention and the control.
Fig 4.
Comparisons of the frequency of asthma exacerbation (the primary endpoint) between the intervention and control group (Fig 4A for overall intervention and control group and Fig 4B for individual strata) during the 12 months prior to the trial and the 12-month trial.
A. Comparison between overall intervention and control group. B. Comparison between intervention and control group at pre-trial and trial by stratum.
Table 2.
Primary and secondary outcomes in intervention and control groups.