Fig 1.
There was no apparent difference in premature study discontinuation for reasons other than death; 23 in the mART arm (2% of 1,227 randomized) and 15 in the iNVP arm (1% of 1217) (p = 0.81). The median (Q1-Q3) follow-up in both arms was to 104 weeks of age (74–105), with a mean of 88 weeks. Most infants still breastfed (93.7% (95%CI: 92.6%, 94.6%)) at 26 weeks of age. The estimated median (Q1-Q3) duration of breastfeeding and, hence, postnatal ARV exposure was 70 weeks (56–82) and not different in both study arms. As previously reported [16], 14 breastfed infants acquired HIV infection during postnatal follow-up (7/1219 mother-infant pairs in the maternal ART arm and 7/1211in the infant NVP arm).
Table 1.
Baseline characteristics for maternal and infant participants in the Postpartum Component.
Table 2.
Summary statistics and comparisons of infant growth measurements by Postpartum Component randomization.
Fig 2.
Infant growth outcomes by assigned study arm.