Fig 1.
Study design and estimated pregnancy trimester of SARS-CoV-2 infection.
Non-infected women (horizontal grey line); SARS-CoV-2 infected women (horizontal fuchsia line); estimated trimester of SARS-CoV-2 infection (horizontal violet line); diagnostic tests to estimate the time of infection (horizontal black line); first reported case of COVID-19 in Piedmont (vertical blue line); consecuitve enrollement of cases at delivery (20 September 2020 to 9 January 2021) and controls at early pregnancy (16 April to 22 June 2020) (square green boxes); time range between the first and the last delivery in the control group, corresponding to the case group consecutive recruitment (time span between dotted and dash-dotted black vertical line); exposure of the entire cohort to SARS-CoV-2 infection (time span between vertical blue line and vertical dash-dotted black line); patients with uncertain seroconversion during pregnancy (asterisk). Abbreviations: Abs, antibodies; NP, nasopharyngeal.
COVID-19 outbreak cases in Piedmont: patient Hospital admission/month.
Table 1.
Baseline characteristics, risk factors for severe SARS-CoV-2 infection, COVID-19 cumulative incidence in the case (preterm births) and the control (full-term births) group.
Table 2.
Case group: Risk factors for preterm birth in SARS-CoV-2-positive and -negative patients.
Table 3.
Case group: Etiopathogenetic factors for preterm birth in SARS-CoV-2-positive and -negative patients.
Table 4.
Delivery mode and neonatal data of the case (preterm births) and the control (full term births) group.