Table 1.
Demographic and clinical characteristics of MS, NMOSD patients, and controls.
Fig 1.
Representative spectral-domain OCT and OCT angiography images of the healthy, MS+ON, and NMOSD+ON eyes.
The eyes with a history of optic neuritis present the ganglion cell complex thinning, more severe in NMOSD+ON eye. Compared with controls, the color-coded flow density maps show a diffuse reduction in superficial capillary plexus, more marked in NMOSD+ON than in MS+ON. The vessel density of the deep capillary plexus is higher in MS+ON than in NMOSD+ON and healthy eye. MS+ON, multiple sclerosis with optic neuritis; NMOSD+ON, neuromyelitis optica spectrum disorder with optic neuritis; OCT, optical coherence tomography.
Table 2.
Baseline spectral-domain OCT and OCT angiography results of patients and controls.
Table 3.
Differences in vessel density and ganglion cell complex thickness between patients and controls.
Table 4.
Comparison of vessel density and ganglion cell complex thickness between selected groups.
Fig 2.
Graphical presentation of spectral-domain OCT and OCT angiography results.
Scatter plots illustrating the linear association between GCC thickness and vessel density of SCP and DCP in patients and controls (A-E). The box plot presents the discrepancy between DCP and SCP of all groups (F). DCP, deep capillary plexus; GCC, ganglion cell complex; OCT, optical coherence tomography; SCP, superficial capillary plexus.