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Fig 1.

Graphical depiction of study design.

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Fig 2.

Flow chart illustrating the inclusion and exclusion of persons into the study.

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Fig 3.

Proportion of anticholinergic burden measured through the Anticholinergic Cognitive Burden (ACB) scale (2016), by sex and age.

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Table 1.

Number and period prevalence of persons with and without anticholinergic burden measured through the Anticholinergic Cognitive Burden (ACB) scale during the observation period (2016), by sex and age.

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Table 2.

Prevalence of use of medications with anticholinergic activity (MACs) in persons with anticholinergic burden measured through the anticholinergic cognitive burden (ACB) scale during the observation period (2016).

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Fig 4.

Median (Q1-Q3) cumulative anticholinergic burden, by sex and age.

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Table 3.

Contribution of anticholinergic medication classes to cumulative anticholinergic burdena in men and women, with at least one dispensation of medication with anticholinergic activity (MAC) during the observation period (2016), by age group.

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Table 4.

Contribution of prescriber specialty to cumulative anticholinergic burdena in men and women, with at least one dispensation of medication with anticholinergic activity (MAC) during the observation period (2016), by sex and age group.

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