Fig 1.
Study flow diagram of patients.
Table 1.
Baseline characteristics of patients (n = 109).
Data are expressed as median (25–75th percentiles) or number (%).
Fig 2.
Receiver operating characteristic (ROC) curves of predictive models for 3-month mortality in 87 critically ill octogenarians.
The continuous line represents the ROC curve of the sequential organ failure assessment (SOFA) score on day 4 after admission to the intensive care unit as a predictor of 3-month mortality. The dashed line represents the ROC curve of the multivariate Cox model including the SOFA score on day 4, neurological failure on admission and the number of preadmission medications as a predictor of 3-month mortality. The area under the ROC curve (AUC-ROC) of the SOFA score on day 4 was 0.72 (95% CI, 0.60 to 0.84), and the AUC-ROC curve of the SOFA score on day 4 with covariates added was 0.81 (95% CI, 0.71 to 0.91).
Table 2.
Multivariate Cox model of mortality on day 90 including SOFA scores adjusted for imputed and independent covariates (primary analysis with 87 patients).
The change in the SOFA score (ΔSOFA) was calculated as SOFA score on day 1 –SOFA score on day 4.
Table 3.
Multivariate Cox model of mortality on day 90 including imputed SOFA scores adjusted for imputed and independent covariates (sensitivity analysis with 109 patients).
The change in the SOFA score (ΔSOFA) was calculated as SOFA score on day 1 –SOFA score on day 4.
Table 4.
Logistic regression model of loss of autonomy for patients who were still alive on day 90 including SOFA scores adjusted for independent covariates (primary analysis with 49 patients).
The loss of autonomy (change in [Δ] ADL) was calculated as ADL score at 90 days–ADL score on day 1, and was defined as ΔADL <0. The change in the SOFA score (ΔSOFA) was calculated as SOFA score on day 1 –SOFA score on day 4.