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Fig 1.

Flow chart of patient participation in the study.

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Table 1.

Baseline demographic and clinical characteristics of the study population comparing non-dialysis CKD and ESKD patients.

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Table 2.

Baseline markers of cognitive function and depression among the study participants comparing non-dialysis CKD and ESKD patients.

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Table 2 Expand

Table 3.

Baseline markers of cognitive function and depression among patients who discontinued the study before follow-up assessment compared to patients who completed follow-up assessment, in the overall sample, CKD and ESKD subgroups.

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Table 4.

Changes in scores of cognitive function and depression between baseline and follow-up for the overall sample and comparison of change scores between non-dialysis CKD and ESKD subgroups.

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Table 5.

Changes in scores of cognitive and psychological measures at follow up compared to baseline for the dialysis cohort and comparison of change scores between patients who commenced dialysis within one year compared to patients who have been on dialysis longer than one year.

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Fig 2.

Change scores of cognitive function and depression in CKD and ESKD patients with fitted regression lines from ANCOVA models using age as a continuous covariate.

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Fig 3.

Change scores of memory, orientation, praxis and executive function domains of cognitive function in CKD and ESKD patients with fitted regression lines from ANCOVA models using age as a continuous covariate.

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Fig 4.

Change scores of cognitive function and depression in ESKD patients with dialysis vintage <1-year and >1-year with fitted regression lines from ANCOVA models using age as a continuous covariate.

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Fig 5.

Change scores of memory, orientation, praxis and executive function domains of cognitive function in ESKD patients with dialysis vintage <1-year and >1-year with fitted regression lines from ANCOVA models using age as a continuous covariate.

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