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Fig 1.

Schematic diagram for the study design.

Note: INR: International Normalized Ratio, TTR: Time to Therapeutic Range.

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Fig 1 Expand

Fig 2.

Flow chart of study cohort selection.

Note: INR: International Normalized Ratio, TTR: Time to Therapeutic Range; NAFLD: Nonalcoholic Fatty Liver Disease; NASH: Nonalcoholic Steatohepatitis; HBV: Hepatitis B Virus Infection, HCV: Hepatitis C Virus Infection.

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Fig 2 Expand

Table 1.

Demographic and clinical characteristics of study population selected from health plan data between 2010 – 2015.

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Table 1 Expand

Table 2.

Demographic and clinical characteristics using propensity score fine stratification, USA 2010 – 2015.

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Table 2 Expand

Fig 3.

Adjusted effect estimate of NAFLD/NASH on average daily dose of warfarin using the propensity score stratification approach after the first 2 months of warfarin use.

Note: NAFLD: Nonalcoholic Fatty Liver Disease; NASH: Nonalcoholic Steatohepatitis; ADD: Average Daily Dose.

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Fig 3 Expand

Fig 4.

Adjusted odds ratio of TTR>60% among NAFLD/NASH vs Non-NAFLD/NASH using the propensity score stratification approach after warfarin initiation.

Note: NAFLD: Nonalcoholic Fatty Liver Disease; NASH: Nonalcoholic Steatohepatitis; TTR: Time to Therapeutic Range.

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Fig 4 Expand