Table 1.
Characteristics of study population at initial visit by gender.
Table 2.
Mean age by child self-reported Tanner stage at third (final) visit.
Table 3.
Mean endocrine marker concentrations at visit 3 by Tanner stage.
Fig 1.
Morning urinary FSH levels in girls by Tanner breast stage and visit.
Girls are classified as pre-pubertal (BS-1), early pubertal (BS-2/3) or late pubertal (BS-4/5) based on self-report of Tanner breast stage at visit 3. P values from repeated measures analysis adjusted for BMI Z-score shown for V3 vs. V1 levels among BS-1 girls (solid), BS-2/3 vs. BS-1 at V1 (dashed) and BS-2/3 vs. BS-1 at V3 (dotted). NS = p≥0.05; *p<0.05; **p<0.01.
Fig 2.
Morning urinary testosterone levels in boys by Tanner genital stage and visit.
Boys are classified as pre-pubertal (GS-1), early pubertal (GS-2/3) or late pubertal (GS-4/5) based on self-report of Tanner genital stage at visit 3. P values from repeated measures analysis adjusted for BMI Z-score shown for V3 vs. V1 levels among GS-1 boys (solid), GS-2/3 vs. GS-1 at V1 (dashed) and GS-2/3 vs. GS-1 at V3 (dotted). NS = p≥0.05; *p<0.05; **p<0.01.
Fig 3.
Salivary DHEA levels in boys by Tanner genital stage and visit.
Boys are classified as pre-pubertal (GS-1), early pubertal (GS-2/3) or late pubertal (GS-4/5) based on self-report of Tanner genital stage at visit 3. P values from repeated measures analysis adjusted for BMI Z-score shown for V3 vs. V1 levels among GS-1 boys (solid), GS-2/3 vs. GS-1 at V1 (dashed) and GS-2/3 vs. GS-1 at V3 (dotted). NS = p≥0.05; *p<0.05; **p<0.01.