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Fig 1.

Directed acrylic graph (DAG).

(A) Reviewing potential relationships associated with inpatient mortality. Key elements detected by the authors included baseline demographics, baseline health characteristics, interventions during hospitalization and severity of disease indicators.

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Table 1.

Univariate analysis.

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Table 1 Expand

Fig 2.

Demographics and clinical characteristics of the patients at baseline.

(A) Model 1a and 1b are binomial logistic regression models with respect to mortality. Lab values were included in 1a, but not 1b. Model 2a and 2b are binomial logistic regression models with respect to mortality within 96 hours of admission. Again, lab values were included in 2a, but not 2b. Demographic information presented represents individuals included in the specified model. Percentages are denoted within parenthesis. Per capita income was determined by patient’s zip code using incomebyzipcode.com. The systemic inflammatory response syndrome score (SIRS) was calculated for hospital admission using the initial white blood cell count, temperature, pulse and respiratory rate present in the ED. Race and ethnicity were self-reported. Values differ due to individuals missing essential data being excluded from the models.

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Fig 3.

Odds ratios for inpatient mortality.

(A) Odds ratios for mortality were determined through binomial logistic regression and are presented with 95 percent confidence intervals. Variables controlled for in the models are included in this table. For race, odds ratios were calculated against those self-reporting as Caucasian, and for insurance, those with commercial insurance.

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Fig 4.

Demographic data for propensitiy score matching of hydroxychloroquine (HCQ) and convalescent plasma (CP) groups.

(A) Propensity score matching was used to create a number of cohorts, and demographics for each cohort are shown in the table above. Model 3a and 3b separate groups with respect to hydroxychloroquine, and model 4a and 4b with respect to convalescent plasma. Percentages of each group are expressed in parenthesis for categorical variables and ranges for continuous. Race and ethnicity are self-reported. Models 3a and 4a included lab values for matching.

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