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Table 1.

SARS-CoV-2 infection likelihood clinical adjudication criteria.

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Fig 1.

Algorithm for determining clinical likelihood of COVID-19 recurrence.

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Fig 2.

Algorithm for determining overall likelihood of COVID-19 recurrence.

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Fig 3.

Interval from initial to recurrent positive SARS-CoV-2 RT-PCR.

Horizontal lines depict the interval from the initial positive SARS-CoV-2 RT-PCR for each patient (N = 114) to their latest repeat positive test occurring at least 60 days subsequently as well as each subject’s clinical probability of COVID-19 recurrence. Individual RT-PCR tests occurring after subject’s initial positive test are shown as closed circles (positive result) and open diamonds (negative result).

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Table 2.

Patient demographic and clinical characteristics.

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Table 2 Expand

Table 3.

Subject characteristics by clinical likelihood of recurrence.

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Table 3 Expand

Fig 4.

SARS-CoV-2 RT-PCR cycle threshold trajectory by clinical recurrence likelihood.

Cycle threshold trajectory for each patient (N = 114) with a recurrent positive SARS-CoV-2 RT-PCR ≥60 days after their initial positive test, stratified by (A) probable (N = 14), (B) possible (N = 30), or (C) unlikely (N = 70) clinical likelihood of COVID-19 recurrence. Abbreviations: Ct, cycle threshold; Neg, negative; RT-PCR, reverse transcription polymerase chain reaction.

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Table 4.

Subject demographic characteristics by cycle threshold trajectory.

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Table 5.

Clinical trajectory with interval negative SARS-CoV-2 RT-PCR or decreasing cycle threshold value on repeat RT-PCR.

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