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Fig 1.

Two representative images of the clinical-CT-mismatch-positive (P group) and clinical-CT-mismatch-negative (N group).

(A) The left panel (the P group) shows a 67-year-old woman with an NIHSS score of 16 and a CT-ASPECTS score of 10 at baseline. After IV thrombolysis, the patient had a good outcome (mRS = 0) at 3 months. (B) The right panel (N group) shows an 81-year-old woman with an initial NIHSS score of 22 and a CT-ASPECTS score of 5. Arrows show hypoattenuation in regions of the lentiform nucleus (L), internal capsule (IC), insula (I), M2, and M3. Although she received IV thrombolytic therapy, her mRS score was 5 at 3 months.

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Fig 1 Expand

Table 1.

Clinical characteristics of patients with cerebral infarction receiving intravenous thrombolysis as classified by clinical-CT mismatch.

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Table 1 Expand

Table 2.

Clinical outcomes of patients with cerebral infarction receiving intravenous thrombolysis as classified by clinical-CT mismatch.

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Table 2 Expand

Table 3.

Favorable outcome (modified Rankin scale ≤1) at 3 months: Dichotomizing ASPECTS scores into clinical-CT Mismatch-positive or clinical-CT Mismatch-negative based on a score of ≥ 7 versus < 7; ≥ 8 versus < 8; and ≥ 9 versus < 9.

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Table 4.

Clinical outcomes of patients with severe (NIHSS > 15) stroke symptoms receiving intravenous thrombolysis: classification by clinical-CT mismatch.

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Table 5.

Multivariate linear regression analysis: The effect of factors on delta NIHSS score (admission NIHSS—baseline NIHSS score).

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Table 6.

Univariate and multivariate logistic regression analysis for predicting the favorable outcome (mRS ≤1).

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