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Fig 1.

Flow of the study.

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Fig 2.

Comparison of MDW among groups with different immune statuses according to Sepsis-3 definition.

(A) All patients. (B) Immune-competent patients. (C) Immune-compromised patients. MDW, monocyte distribution width.

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Table 1.

Baseline clinical characteristics of patients visiting the emergency department.

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Table 2.

Comparison of biomarker levels according to Sepsis-3 definition.

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Fig 3.

AUC of ROC curve for sepsis prediction, according to immune status.

(A) Comparison of AUROC in the overall population. WBC count alone is inferior to other biomarkers. (B) Comparison of AUROC in immune-compromised patients. (C) Comparison of AUROC in immune-competent patients. AUROC is relatively higher in immune-competent patients. ROC, receiver operating curve; AUC, area under the curve; AUROC, area under the curve of receiver operating curve; MDW, monocyte distribution width; CRP, C-reactive protein; PCT, procalcitonin; WBC, white blood cell.

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Table 3.

Diagnostic performance of WBC count, CRP, PCT, and MDW in predicting sepsis (by Sepsis-3 definition).

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Table 3 Expand

Table 4.

Diagnostic performance of WBC count, CRP, PCT, and MDW for predicting sepsis according to immune status.

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Table 5.

Comparison of discriminative performance of biomarkers combined with qSOFA.

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