Fig 1.
The spectrum of disease in the diffuse midline glioma patients with K27M mutation in MRI.
In the upper row (a1, a2, a3, a4) examples of mass verification with T2-weighted FLAIR imaging are shown. In the middle row (b1, b2, b3, b4) the same cases with unenhanced T1-weighted imaging can be seen, and in the lower row (c1, c2, c3, c4) these patients are presented with T1-weighted imaging following contrast material administration—exhibiting the spectrum of contrast enhancement patterns from almost absent to rim enhancing. However, as a possible hallmark—edema in this entity is frequently absent.
Table 1.
Patients’ characteristics including demography, genetic and histological findings, steroid therapy at the time of imaging and analysis of these features in relation to tumor type.
Table 2.
Summary of imaging findings and analysis of their difference in relation to tumor type using Fisher’s exact test.
Table 3.
Analysis of peritumoral edema and strong contrast enhancement using logistic regression models.