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Fig 1.

[Aneuploid Cohort: Clinical + Research specimens] composition of specimens included in the Aneuploid Cohort.

C = Clinical specimens; R = Research specimens.

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Fig 2.

[Y Cohort: Clinical + Research specimens] composition of specimens included in the Y Cohort.

C = Clinical specimens; R = Research specimens.

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Table 1.

[Aneuploid Cohort: Clinical + Research specimens] comparison of aneuploid chromosome mosaicism ratio among affected singletons, two affected twins, and one affected twin, by aneuploidy.

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Table 2.

[Aneuploid Cohort: Clinical + Research specimens] distribution of aneuploid MR by trisomy.

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Table 3.

[Y Cohort: Clinical + Research specimens] comparison of Y chromosome mosaicism ratio between XX/XY and XY/XY twins in euploid, aneuploid, and combined cases.

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Table 4.

[Y Cohort: Clinical + Research specimens] probability of XX/XY versus XY/XY outcome based on Y MR when Y chromosome material is detected.

Includes only euploid cases.

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Table 5.

Accuracy of twin fetal sex prediction (XX/XY vs. XY/XY outcome when Y material is detected) in euploid gestations at various Y MR cutoffs.

Analysis based on Y MRs from 98 euploid samples.

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Table 6.

[Y Cohort: Clinical + Research specimens] probability of XX/XY versus XY/XY outcome based on Y MR when Y chromosome material is detected.

Includes euploid and aneuploid cases.

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Table 6 Expand

Table 7.

[Aneuploid Cohort: Clinical specimens] triplet cases with positive cfDNA results and outcome information.

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Table 8.

[Y Cohort: Research specimens] cfDNA and diagnostic information for triplet and quadruplet research specimens.

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