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Fig 1.

CONSORT diagram.

Study enrolment and randomisation.

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Fig 1 Expand

Fig 2.

Study design & treatment procedure: Patients were instructed to self-administer the treatment bilaterally on the neck three times per day for two weeks at home.

The treatment was delivered via two stainless steel contact surfaces that were covered with conductive gel before each treatment.

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Fig 2 Expand

Table 1.

Demographic and clinical characteristics of chronic pancreatitis patients.

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Table 1 Expand

Fig 3.

Average pain score during the two study periods for the two sequences (nVNS/sham in black and sham/nVNS in grey). VAS = visual analogue scale.

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Fig 3 Expand

Table 2.

Primary and secondary clinical endpoints after two weeks of nVNS and sham treatment.

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Table 2 Expand

Table 3.

Patient’s Global Impression of Change (PGIC).

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Table 3 Expand

Table 4.

Adverse events.

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Table 4 Expand