Fig 1.
1H NMR fragments of the spectrum of a volunteer urine sample collected before (blue) and 2 hours after the administration of 3000 mg of the ACA (red).
Fig 2.
Overlay of COSY spectra of urine before (red) and post-dose (green) after the administration of 3000mg of ASA.
Fig 3.
1H NMR spectra of urine samples from a healthy volunteer, collected before (blue) and 4 hours after the administration of 100mg ASA (red).
Fig 4.
1H NMR fragment of the spectrum of a urine sample collected after the administration of 100 mg of the drug.
The spectrum is compared to the spectra of salicylic and salicyluric acid (a) and with the spectrum of hippuric acid (b).
Fig 5.
The fragment of HOMO2D spectrum in the region from 8.5 to 6.0 ppm of urine sample from participant after the administration of 300mg of ASA.
Fig 6.
Fragments of 1H NMR spectra of urine samples collected before (a) and after the administration of 100 mg of aspirin (b).
Urine samples were collected 4 hours post-dose for volunteers No.1 and No.2, and 3 hours for volunteer No.2.