Fig 1.
Pairwise metabolism comparison of different organisms: Overall view of the proposed methodology.
Fig 2.
A two-level view of the metabolism: The Structural level (yellow background) and the Functional level (green background).
Table 1.
List of KEGG metabolic categories: Each one is composed by many metabolic pathways.
Table 2.
Summary of local similarity indexes.
Table 3.
Summary of global similarity indexes.
Fig 3.
Organisms selection window: Example for api and bap.
Fig 4.
Comparison results for api and bap.
Fig 5.
Visual comparison of api and bap at the structural level: (a) api metabolic network; (b) bap metabolic network; (c) api-bap topology comparison; (d) Glyoxylate & dicarboxylate metabolism pathway connections; (e) Methane metabolism pathway connections.
Table 4.
Yeasts and Molds considered in the second experiment.
Fig 6.
Clustering obtained in the Yeasts and Molds experiment for the pathway similarity index.
Fig 7.
Color map visualization of similarity matrices of the Mammals metabolism experiment: Lighter colors correspond to organisms with high degree of similarity (from yellow to blue).
Rows and colums are labeled according to the organisms ids 0–65 listed in S1 Table.