Fig 1.
Experimental design of the rest-task-rest paradigm (RTR) which includes two resting-state conditions (pre- and post-task resting-state, R1 and R2) and the task condition composed of three subtasks (passive (T1), count (T2) and response (T3)) of the visual oddball paradigm (VOP).
Table 1.
Description of parameters used to examine the effect of the task on the fMRI measures in the post-task RS.
Fig 2.
Depiction of the triple networks referred to as the triple network: Default mode network (DMN, blue colour), central executive network (CEN, red colour), and salience network (SN, green colour). The networks were identified by decomposing the pre-task resting-state condition into 20 components from 21 subjects.
Table 2.
Mean values and standard deviations (SD) of the three fMRI measures during the two RS periods (R1 and R1) and the three subtasks of the VOP (T1, T2 and T3) obtained from the triple network (default mode network (DMN), salience network (SN), and central executive network (CEN)), based on the mean values of each parameter in 21 subjects.
Fig 3.
fMRI measures (ALFF, ReHo, and DC) from 21 subjects depicted for the whole brain.
The difference between the two resting states (R2-R1) for each three fMRI measures is shown in the right row (B).
Fig 4.
Bar chart representing the mean of the fMRI measures—amplitude of low-frequency fluctuations (ALFF), the regional homogeneity (ReHo), and the degree centrality (DC) in the three resting state networks—default mode network (DMN) (A), central executive network (CEN) (B) and salience network (SN) (C)- across 21 subjects in 5 conditions including resting-state 1 (R1), passive (T1), count (T2), respond (T3), and resting-state 2 (R2).
Fig 5.
Strength of the FC between each pair of networks in the triple network in the pre- and post-task resting-state.
There is a significant increase in FC between the DMN and CEN, and between the CEN and the SN in the post-task resting-state (p < 0.05). The bars represent the standard error.
Fig 6.
Correlations between the fMRI measures resulting from the pure task(whole) effects and the RSD in the triple network, including the DMN, CEN, and SN of the fMRI measures.
Table 3.
Mean values, standard deviation, and the range of the resting-state similarity (RSS) calculated separately for each resting-state fMRI parameter (ALFF, ReHo, and DC) and for each of the triple networks (default mode network (DMN), salience network (SN), and central executive network (CEN).
Table 4.
The relationships between the fMRI measures (ReHo, and DC) across the brain networks (DMN, CEN, and SN).
All correlations coefficients were positive and significant at p < 0.01.