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Fig 1.

ROIs position for CNR evaluation in the CTP404 module of the Catphan-504 phantom.

The depicted ROIs refer to the LDPE contrast insert.

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Table 1.

CT scanners enrolled in the study.

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Table 2.

Nominal HU values of the Catphan-CTP404 module inserts [58].

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Table 3.

Clinical head CT imaging protocols used for each scanner by the staff of various Radiology/Neuroradiology departments at the Pisa university hospital.

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Table 4.

Noise (σ) values (mean ± standard deviation across five repeated measurements), for each CT scanner/acquisition protocol.

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Fig 2.

Noise power spectrum (NPS) of images acquired using different CT scanners/acquisitions protocols.

Panels A, B, C, D and E show the NPS curves (mean ± standard deviation across five repeated measurements) for Toshiba-16, GE-16RT, GE-64VCT, Siemens-64 and GE-128 scanners, respectively. In order to better compare the different NPS curves, panel F shows on the same graphic the NPS curves for all scanners/acquisition protocols.

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Table 5.

Peak position of NPS curves for each CT scanner/acquisition protocol.

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Table 6.

CNR values (mean ± standard deviation across five repeated measurements) of different inserts from the CTP404 phantom, for each CT scanner/acquisition protocol.

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Fig 3.

Modulation transfer function (MTF) curves of images acquired using different CT scanners/acquisitions protocols.

Panels A, B, C, D and E show the MTF curves (mean ± standard deviation across five repeated measurements) for Toshiba-16, GE-16RT, GE-64VCT, Siemens-64 and GE-128 scanners, respectively. In order to better compare the different MTF curves, Panel F shows on the same graphic the MTF curves for all scanners/acquisition protocols, with a zoomed in version for the 40%-60% range of MTF.

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Table 7.

Spatial frequencies (mean ± standard deviation across five repeated measurements) corresponding to 50% (f50%) and 10% (f10%) of the MTF curves, for each CT scanner/acquisition protocol.

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Fig 4.

Low-contrast detectability (LCD) curves of images acquired using different CT scanners/acquisition protocols.

Panels A, B, C, D and E show the LCD curves (mean ± standard deviation across five repeated measurements) for Toshiba-16, GE-16RT, GE-64VCT, Siemens-64 and GE-128 scanners, respectively. In order to better compare the different LCD curves, Panel F shows on the same graphic the LCD curves for all scanners/acquisition protocols.

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Table 8.

NUI values (mean value ± standard deviation across five repeated measurements) for each CT scanner/acquisition protocol.

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