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Table 1.

Inclusion and exclusion criteria.

These criteria were used during the screening of abstracts and then full texts.

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Fig 1.

Search flow diagram.

BOT = burden of treatment, PROM = patient-reported outcome measure.

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Table 2.

Characteristics of the studies presented in the articles included.

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Table 2 Expand

Table 3.

Assessment of the intervention in the included articles.

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Table 3 Expand

Table 4.

Quality and risk of bias assessment.

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Table 4 Expand