Fig 1.
(A) Schematic of the RapidVent connected to oxygen source (green arrow) and to the patient. A single tube carries the inhaled and exhaled air (pink arrow). (B) Photograph of the RapidVent prototype that was used for the various tests in this study. The middle transparent section and the manometer dial are off the shelf parts.
Fig 2.
Training materials showing the steps of using the RapidVent.
Fig 3.
CAD (top) and photographs (bottom) of the various parts of the RapidVent prototype. (1) Connection to O2 and FiO2 air entrainment nozzle; (2) pop-off pressure relief valve; (3) one-way valve; (4) connection to patient; (5) connection to the rest of the ventilator; (6) Peak Inspiratory Pressure (PIP) dial; and (7) rate dial.
Fig 4.
Principle of operation of the RapidVent.
(A) Cross section of the modulator design. (1) The breathing rate dial and exhaust port. (2) The Peak Inspiratory Pressure (PIP) dial. (3) Linear spring. (4) Passive pressure relief holes. (5) The diaphragm. (6) The modulator tube. (7) The modulator enclosure. (B) Schematic showing the mechanism of pressure-driven ventilation during inhalation (left) and exhalation (right). During inhalation, the modulator tube is sealed by the diaphragm. After the PIP is reached, the diaphragm moves up allowing exhalation to start. The lung pressure is released until the Positive End Expiratory Pressure (PEEP) value is reached. At the PEEP point, the diaphragm moves back down and seals the tube. The cycle repeats. (C) Pressure versus time during the inhalation (left) and exhalation (right) half cycles.
Fig 5.
The testing setup and measured performance of the RapidVent.
(A) Schematic of the testing setup. “T” and “P” refer to temperature and pressure sensors. (B) Pressure measured between the ventilator and the test lung versus time on the RapidVent (left) and a commercial EV for reference (right). (C) Flow rate measured between the ventilator and the test lung versus time on the RapidVent (left) and the reference device (right). BPM is Breaths Per Minute.
Fig 6.
Performance of the RapidVent during simulation of its use in various clinical scenarios.
(A) Pressure versus time when the ventilator operates at PIP of 40 cm-H2O and 32 BPM, and (B) PIP of 25 cm-H2O at 15 BPM.
Fig 7.
(A) Schematic of the setup used during the mechanical ventilation of sedated pigs. (B) Example of the breath cycles of the animal induced by the RapidVent when the PIP is set to 20 cm-H2O at 16 BPM.
Fig 8.
Overview of electronic monitoring system.
(A) System diagram showing pressure sensor input from RapidVent. (B) Photograph of alarm with display connected to Drager test lungs. (C) Data from Drager test lung showing different alarm conditions. The measured pressure is p and the envelopes vhigh and vlow are used to track the breath cycle. The noncycling alarm is triggered when the pressure envelopes are too close together.